There are many different types of cancer such as leukemia, breast cancer, and melanoma. This means that there are many different warning signs to look out for. However, if you figure out that you or a loved one has cancer, there are plenty of treatment options to consider. Cancer drugs like Eribulin, Omacetaxine, and Vorinostat can work to treat cancer in a variety of patients. Specifically, AYVAKIT® (avapritinib) for unresectable or metastatic gastrointestinal stromal tumor (GIST) is an option for those with GIST to consider. Additionally, various therapies are available to treat cancer such as hormone therapy, immunotherapy, radiation therapy, and more. If you or your loved one has cancer, it’s important to consult with a medical professional about tailoring the best possible treatment plan. Otherwise, if you suspect that you or your loved one may have cancer, here are 4 early warning signs to keep an eye out for:

1. Pain

While this warning sign is very general and can, of course, be caused by any number of things—various conditions, illnesses, lifestyle choices, and more—pain can also be caused by cancer. The disease can result in different types of pain due to the chemicals that a cancer releases, the spread of cancer throughout the body—also known as metastasis—and a tumor or mass putting pressure on another area of the body. Experiencing persistent pain is always worth getting checked out by a medical professional, whether the underlying cause is cancer or otherwise.

2. Skin changes

There are various skin changes that can be early warning signs of cancer. Jaundice—also known as the yellowing of the fingertips or eyes—is one of these, while noticeable changes in a mole is another. For the latter, it’s best to contact a medical professional if a mole is large or growing larger, has changed color or is getting darker, is asymmetrical or has jagged edges, or has irregular borders.

3. Fatigue

Plenty of us know how it feels to be exhausted after an all nighter. Fatigue, however, differs from the typical exhaustion that many of us are accustomed to: if your tiredness refuses to ebb away with sleep or rest, this could be an early warning sign of cancer. Since cancer uses the nutrients present within the body to grow, the nutrients that your system is used to having are no longer readily available, thus resulting in fatigue.

4. Blood in the stool

If you notice blood in your stool, this is usually coming from somewhere in the stomach, intestines, esophagus, or GI tract. While bright red blood can indicate an issue in the rectum or end of intestines, dark red blood can indicate an issue located higher up, such as somewhere in the stomach. Finding blood in the stool can be a sign of cancer, but it could also be a sign of many other conditions such as stomach ulcers, hemorrhoids, and more. No matter what, it’s important to reach out to a medical professional if you notice blood in your stool.